Greppone Mazzi is the estate where Ruffino produces its Brunello di Montalcino.

The estate is located east of the small town of Montalcino, in the heart of the historical Brunello production area. With its altitude of 450-500 meters above sea level, this is the most elevated part of the hill which constitutes the DOCG of Montalcino. This area is known as "dei Greppi" because of its landscape formed by steep, rugged hills.

The estate extends on 120 hectares of land, where vines (13.5 hectares), olive trees, forests, and wheat fields form a patchwork landscape around the estate villa.